The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Mar. 14, 2013
Applicant:
Shire Human Genetic Therapies, Inc., Lexington, MA (US);
Inventors:
Hongsheng Xie, Acton, MA (US);
Brian Felice, Wellesley, MA (US);
Thomas McCauley, Cambridge, MA (US);
Assignee:
Shire Human Genetic Therapies, Inc., Lexington, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 9/0019 (2013.01); A61K 38/46 (2013.01); C12Y 301/06013 (2013.01);
Abstract
The present invention provides, among other things, compositions, kits and methods for subcutaneous delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention provides methods for treating Hunter syndrome by subcutaneous administration of a replacement iduronate-2-sulfatase (I2S) protein. In some embodiments, the present invention provides a kit comprising an arrangement of components for subcutaneously administering iduronate-2-sulfatase (I2S) protein.