Company Filing History:
2 out of 2,009 
1 out of 1,307 
Years Active: 2006-2011
Title: Innovations of Brian E Applegate
Introduction
Brian E Applegate is a notable inventor based in Durham, NC (US). He has made significant contributions to the field of optical coherence tomography (OCT) through his innovative methods and systems. With a total of 2 patents, Applegate's work has advanced the capabilities of imaging technologies.
Latest Patents
Applegate's latest patents include "Methods, systems, and computer program products for performing real-time quadrature projection based Fourier domain optical coherence tomography." This patent discloses a method where a plurality of interferogram signals is phase shifted, and a Fourier transform is applied to each signal. The depth dependence of the transformed signals is removed, allowing for the calculation of real and imaginary quadrature components. These components are combined to construct a full-range depth profile of the object, ultimately generating a comprehensive depth image.
Another significant patent is the "Method for optical coherence tomography imaging with molecular contrast." This method determines spatial information about a specific molecular contrast agent by stimulating a sample containing the agent. The resulting optical property changes allow for the profiling of the molecular contrast agent concentration distribution through acquired OCT images.
Career Highlights
Throughout his career, Brian E Applegate has worked with prestigious institutions such as Duke University and Case Western Reserve University. His research has focused on enhancing imaging techniques, particularly in the realm of optical coherence tomography.
Collaborations
Applegate has collaborated with notable colleagues, including Joseph A Izatt and Divakar K Rao. These partnerships have contributed to the advancement of his research and the development of innovative imaging solutions.
Conclusion
Brian E Applegate's contributions to the field of optical coherence tomography have paved the way for advancements in imaging technologies. His innovative patents and collaborations highlight his commitment to enhancing scientific understanding through technology.