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For the Inventor, By the Inventor

Medford, MA, United States of America

Brian D Kelley

This inventor holds 14 USPTO granted patents, plus 2 CIPO patents and 4 EPO patents, primarily in Protein Purification. Top assignees: Dyax Corporation, Wyeth, Genetics Institute, Inc.. Active years: 1996-2017.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Brian D Kelley. Retrieved from https://idiyas.com/inventor/brian-d-kelley

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 14

% Patents Active = 85.7



Average Co-Inventor Count = 4.6

ph-index = 4

Forward Citations = 199(Granted Patents)


Company Filing History:

goldMedal6 out of 175 
 
Dyax Corporation
 patents
silverMedal4 out of 1,309 
 
Wyeth
 patents
bronzeMedal3 out of 392 
 
Genetics Institute, Inc.
 patents
4. 1 out of 834,659 
Other
 patents

Years Active: 1996-2017

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Areas of Expertise:
Hydroxyapatite Chromatography
Factor VIII
Protein Purification
Binding Molecules
Polypeptides
Osteogenic Proteins
Weak Partitioning
Human Factor VIII
Protein Delivery
Compositions
Methods
Fragements
14 patents (USPTO):Explore Patents
1. 9822143 - Removal of high molecular weight aggregates using hydroxyapatite chromatography (2017-11-21),
2. 9469672 - Removal of high molecular weight aggregates using hydroxyapatite chromatography (2016-10-18),
3. 9156883 - Binding molecules for human factor VIII and factor VIII-like proteins (2015-10-13),
4. 9144755 - Method of weak partitioning chromatography (2015-09-29),
5. 8535892 - Binding molecules for human factor VIII and factor VIII-like proteins (2013-09-17),
6. 8067182 - Method of weak partitioning chromatography (2011-11-29),
7. 8058017 - Methods and compositions for purifying human factor VIII, factor VIII-like proteins or fragments thereof (2011-11-15),
8. 7820796 - Methods for producing Factor VIII proteins (2010-10-26),
9. 7691565 - Binding molecules for human factor VIII and factor VIII-like proteins (2010-04-06),
10. 7112438 - Binding molecules for human factor VIII and factor VIII-like proteins (2006-09-26),
11. 6683159 - Methods for producing factor VIII proteins (2004-01-27),
12. 6492105 - Binding molecules for human factor VIII and factor VIII-like proteins (2002-12-10),
13. 6197526 - Polypeptides for binding human factor VIII and fragments of human factor VIII (2001-03-06),
14. 5520923 - Formulations for delivery of osteogenic proteins (1996-05-28),

Title: **Brian D. Kelley: Innovator in Antibody Purification Technologies**

Introduction

Brian D. Kelley, an accomplished inventor based in Medford, MA, has made significant contributions in the field of biochemistry. With a portfolio boasting 14 patents, Kelley has pioneered methods that enhance the purification of antibodies, which are crucial for therapeutic and diagnostic applications.

Latest Patents

Among Kelley's notable inventions is his patent on the "Removal of High Molecular Weight Aggregates Using Hydroxyapatite Chromatography." This inventive process involves the application of hydroxyapatite chromatography to purify antibodies from preparations containing high molecular weight aggregates. By integrating ceramic hydroxyapatite chromatography into a combination chromatographic protocol, Kelley has improved the efficiency of antibody purification, which is vital for producing high-quality therapeutic agents.

Career Highlights

Brian D. Kelley has worked with prominent companies in the biopharmaceutical industry, including Dyax Corporation and Wyeth. His experience in these organizations has undoubtedly influenced his innovative approaches to antibody purification.

Collaborations

Throughout his career, Kelley has collaborated with distinguished colleagues such as James Edward Booth and Jinan Yu. These partnerships have fostered an environment of creativity and innovation, leading to advancements in biochemistry and protein purification techniques.

Conclusion

Brian D. Kelley stands out as a key figure in the field of antibody purification, with an impressive patent portfolio that reflects his commitment to innovation. His work continues to impact the biotechnology sector, ensuring the development of effective therapeutic solutions.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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