Braeden L Butler is an accomplished inventor based in Madison, WI (US). He has made significant contributions to the field of biosensors and live cell applications. With a total of 13 patents to his name, Butler's work is at the forefront of innovative technologies.

Latest Patents

Among his latest patents is the development of pro-substrates for live cell applications. These pro-substrates are designed to be useful in assays of living cells, allowing for the detection of enzymes such as luciferase. The pro-substrates can be derivatives or analogs of coelenterazine. Another notable patent is for mutant protease biosensors with enhanced detection characteristics. This invention includes a polynucleotide encoding a biosensor polypeptide that features a modified circularly-permuted thermostable luciferase. The design includes a linker that connects the C-terminal and N-terminal portions of the thermostable luciferase, enhancing the response of the biosensor upon interaction with target molecules.

Career Highlights

Braeden L Butler is currently employed at Promega Corporation, where he continues to innovate and develop new technologies. His work has had a significant impact on the field of biosensing and live cell assays.

Collaborations

He collaborates with talented coworkers, including Frank Fan and Brock Binkowski, who contribute to the innovative environment at Promega Corporation.

Conclusion

Braeden L Butler's contributions to the field of biosensors and live cell applications highlight his role as a leading inventor. His patents reflect a commitment to advancing technology and improving scientific research.

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