Bolor Tumurpurev

Title: Bolor Tumurpurev: Innovator in Polynucleotide Detection

Introduction

Bolor Tumurpurev is a distinguished inventor based in Washington, DC. He has made significant contributions to the field of molecular biology, particularly in the detection of target polynucleotides. With a total of 2 patents to his name, Tumurpurev's work is paving the way for advancements in genetic research and diagnostics.

Latest Patents

Tumurpurev's latest patents include innovative methods for detecting target polynucleotides. The first patent, titled "Exonuclease Cycling Assay," describes a novel method that involves hybridizing a target polynucleotide with a probe to form a hybrid. This hybrid is then exposed to a 5' exonuclease, which digests the probe and dissociates the target polynucleotide. By repeating the hybridization and digestion steps, the presence of digested probes can be detected, indicating the presence of the target polynucleotide.

The second patent, "Polymerase Driven NESA," outlines a method that begins with exposing the target polynucleotide to an initiating oligonucleotide. This oligonucleotide is extended with a sequence complementary to the target, and then ligated to form a circular oligonucleotide. The circular oligonucleotide is exposed to a DNA polymerase and a DNA synthesis primer, leading to the synthesis of DNA with a nicking endonuclease (NE) recognition sequence. The synthesized DNA is then exposed to a probe, forming a double-stranded DNA that is cleaved by a nicking endonuclease. The detection of the cleaved probe indicates the presence of the target polynucleotide.

Career Highlights

Bolor Tumurpurev is affiliated with Georgetown University, where he continues to engage in groundbreaking research. His work has garnered attention for its potential applications in various fields, including medical diagnostics and genetic engineering.

Collaborations

Throughout his career, Tumurpurev has collaborated with notable colleagues, including Mark Danielsen and Berenice Alfonso. These collaborations have further enriched his research and contributed to the advancement of innovative methodologies in molecular biology.

Conclusion

Bolor Tumurpurev is a prominent figure in the realm of polynucleotide detection, with a focus on developing novel methods that enhance the accuracy and efficiency of genetic