Cary, NC, United States of America

Bo H Arve


Average Co-Inventor Count = 13.0

ph-index = 2

Forward Citations = 19(Granted Patents)


Company Filing History:


Years Active: 2001-2007

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4 patents (USPTO):Explore Patents

Title: Bo H Arve: Innovator in Protein Solubility and Formulation

Introduction

Bo H Arve, an accomplished inventor based in Cary, NC, has made significant contributions to the field of biochemistry, particularly in the realm of protein solubility and formulation. With a total of four patents to his name, he is recognized for his innovative approaches to enhancing the preparation of pharmaceutical compositions.

Latest Patents

Bo H Arve's latest patents focus on the formulation, solubilization, purification, and refolding of tissue factor pathway inhibitors (TFPI). One notable patent describes compositions that facilitate the formulation of TFPI through the use of solubilizers and stabilizers. These compositions are capable of achieving various concentrations of TFPI, offering promising applications in pharmaceutical settings. Another innovative patent introduces a method for modifying protein solubility utilizing polyionic polymers, which effectively assist in the solubilization, purification, and refolding of proteins, particularly those that have been incorrectly folded or aggregated. These advancements allow the preparation of pharmaceutically acceptable TFPI compositions at concentrations exceeding 0.2 mg/mL and up to 10 mg/mL.

Career Highlights

Throughout his career, Bo H Arve has worked with several organizations, including G.D. Searle LLC, where he further developed his expertise in protein formulation and biopharmaceutical applications. His efforts have significantly impacted the field, providing valuable solutions for protein solubility issues that are crucial for therapeutic development.

Collaborations

Arve has collaborated with notable professionals such as Glenn J Dorin and Gregory L Pattison. These partnerships have fostered an environment of innovation, enabling the exchange of ideas that have led to the development of his patents.

Conclusion

In conclusion, Bo H Arve stands out as a dedicated inventor who has contributed to advancements in the formulation and solubilization of proteins. His innovative patents showcase his commitment to enhancing pharmaceutical applications and improving the efficacy of protein-based therapies, reinforcing his position as a leading figure in this specialized field.

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