Company Filing History:
Years Active: 2002
Title: Bharat Biswal: Innovator in MRI Technology
Introduction
Bharat Biswal is a prominent inventor based in Milwaukee, WI (US), known for his significant contributions to the field of MRI technology. With a total of 2 patents, he has made strides in developing methods that enhance the understanding of brain functionality and diseases such as Alzheimer's.
Latest Patents
His latest patents include an innovative MRI system and method for producing an index indicative of Alzheimer's disease. This method involves acquiring time course MRI data from the hippocampal region of the brain, which is then processed to produce an index that measures functional connectivity between various locations within the hippocampus. The MRI data is collected while the brain is at rest, and the spontaneous low-frequency component of the time course data is extracted and analyzed through a cross-correlation process.
Another notable patent is a method for determining the reliability of fMRI parameters. In this process, an EPI pulse sequence is performed by an MRI system to acquire images of the brain over a time interval while the subject performs a function or is stimulated in a specific pattern. An fMRI parameter is calculated for each voxel, indicating active regions of the brain during the study. The same acquired NMR data is utilized in a jackknife method to recalculate the fMRI parameter multiple times, producing a confidence level indicator from the distribution of recalculated values. Low confidence level indicators are then used to exclude regions that are otherwise indicated as active.
Career Highlights
Bharat Biswal is currently associated with the MCW Research Foundation, Inc., where he continues to push the boundaries of MRI technology. His work has been instrumental in advancing the understanding of brain connectivity and the reliability of fMRI parameters.
Collaborations
He collaborates with esteemed colleagues such as John L Ulmer and Shi-Jiang Li, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Bharat Biswal's contributions to MRI technology and his innovative patents reflect his dedication to advancing medical imaging and understanding brain functionality. His work continues to have a significant impact on the field, paving the way for future research and developments.