Mcw Research Foundation, Inc.

Bharat Biswal

John L Ulmer

James Stewart Hyde

Shi-Jiang Li

Piero Antuono

Zhu Li

Zerrin F Yetkin

Paul A Taylor

Time course MRI data is acquired from the hippocampal region of the brain and processed to produce an index which is a measure of the functional connectivity between locations therein. The MRI data is acquired while the brain is substantially at rest and the spontaneous low frequency component of the time course data at each location in the hippocampus is extracted and compared in a cross-correlation process.

MRI system and method for producing an index indicative of alzheimer's disease

An EPI pulse sequence is performed by an MRI system which acquires images of the brain over a time interval during which the subject performs a function or is stimulated in a pattern. An fMRI parameter is calculated for each voxel which indicates those regions of the brain that are active during the study. The same acquired NMR data is employed in a jackknife method for recalculating the fMRI parameter many times and from the distribution of the recalculated values a confidence level indicator is produced. Low confidence level indicators are used to exclude regions which are otherwise indicated as active.

Method for determining the reliability of fMRI parameters

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Milwaukee, WI, United States of America

Bharat Biswal