Bertrand Schwartz

Title: Bertrand Schwartz: Innovator in Cardiac Gene Therapy

Introduction

Bertrand Schwartz is a notable inventor based in Jouy en Josas, France. He has made significant contributions to the field of cardiac gene therapy, particularly through his innovative work on gene expression control.

Latest Patents

Schwartz holds a patent for "Sequences upstream of the CARP gene, vectors containing them and uses thereof." This invention relates to novel promoter sequences derived from a portion upstream of the coding sequence of the gene for the CARP protein (Cardiac Ankyrin Repeat Protein). These sequences are capable of controlling the level and specificity of transgene expression in vivo in cardiac muscle cells. The invention describes novel compositions, constructs, vectors, and their uses for the transfer and expression of nucleic acids in cardiac muscle cells. Additionally, the patent outlines the use of these promoter sequences for generating transgenic animals that serve as models for studying certain cardiac pathologies.

Career Highlights

Throughout his career, Schwartz has worked with prominent organizations, including Centelion and the University of California. His work has focused on advancing the understanding and treatment of cardiac conditions through innovative genetic approaches.

Collaborations

Some of his notable coworkers include Patrick Benoit and Didier Branellec. Their collaborative efforts have contributed to the advancement of research in cardiac gene therapy.

Conclusion

Bertrand Schwartz's contributions to cardiac gene therapy through his innovative patent and collaborations highlight his role as a key figure in the field. His work continues to pave the way for advancements in understanding and treating cardiac diseases.