The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Dec. 07, 2001
Patrick Benoit, Paris, FR;
Bertrand Schwartz, Jouy En Josas, FR;
Didier Branellec, Brie-Comte-Robert, FR;
Kenneth R. Chien, La Jolla, CA (US);
Ju Chen, San Diego, CA (US);
Patrick Benoit, Paris, FR;
Bertrand Schwartz, Jouy En Josas, FR;
Didier Branellec, Brie-Comte-Robert, FR;
Kenneth R. Chien, La Jolla, CA (US);
Ju Chen, San Diego, CA (US);
Centelion, , FR;
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention relates to novel promoter sequences derived from a portion upstream of the coding sequence of the gene for the CARP protein (Cardiac Ankyrin Repeat Protein), and which are capable of controlling the level and the specificity of expression of a transgene in vivo in cardiac muscle cells. The invention thus describes novel compositions, constructs, vectors and their uses in vivo for the transfer and expression of a nucleic acid in vivo in cardiac muscle cells. The subject of the present invention is also the use of the promoter sequences for generating transgenic animals which constitute models for studying certain cardiac pathologies.