Bertrand Pain

Title: Bertrand Pain: Innovator in Avian Cell Line Technology

Introduction

Bertrand Pain is a notable inventor based in Lyons, France, recognized for his contributions to the field of avian cell line technology. With a total of 6 patents, Pain has made significant advancements that facilitate the replication of avian viruses, which are crucial for vaccine development.

Latest Patents

One of Pain's latest patents is a method for selecting a permissive cell line for replicating avian viruses. This invention outlines a systematic approach to obtain an untransformed avian cell line that enables in vitro replication of avian viruses. The method involves several steps, including culturing avian embryonic stem cells in the presence of a stroma, followed by a series of specific culture conditions that ultimately lead to the establishment of a cell line suitable for virus replication. Another significant patent is a method of making an avian cell line, which focuses on the gradual or complete withdrawal of growth factors and serum to create adherent or nonadherent cells capable of indefinite proliferation in a basic culture medium. This innovation is particularly valuable for producing substances of interest.

Career Highlights

Throughout his career, Bertrand Pain has worked with esteemed research institutions, including the National Institute for Agronomic Research and the National Center for Scientific Research. His work has been instrumental in advancing the understanding and application of avian cell lines in scientific research and vaccine production.

Collaborations

Pain has collaborated with various professionals in his field, including Fabienne Guehenneux, enhancing the impact of his research through shared expertise and knowledge.

Conclusion

Bertrand Pain's innovative work in avian cell line technology has paved the way for significant advancements in vaccine development and virology. His contributions continue to influence the scientific community and improve public health outcomes.