This inventor holds 1 USPTO granted patent. Top assignee: Pharis Biotec Gmbh. Active years: 2001.
Company Filing History:
Years Active: 2001
Title: Bernhard Brenner: Innovator in Genetic Diagnostics
Introduction
Bernhard Brenner is a notable inventor based in Hanover, Germany. He has made significant contributions to the field of medical diagnostics, particularly in the detection of genetically caused pathogenic point mutations. His innovative approach has the potential to enhance the accuracy and efficiency of genetic testing.
Latest Patents
Brenner holds a patent for a method titled "Method for the direct diagnostic detection of genetically caused pathogenic point mutations." This invention relates to a quick method for the qualitative and quantitative medical-diagnostic analysis on the protein level of the substitution of single amino acids with pathogenic and non-pathogenic effects on the organism. The medical-diagnostic analysis is performed through a combination of enzymatic or chemical cleavage of the isolated peptide, chromatographical separation of the fragments, and analysis by mass spectrometry, including both direct LC/MS and indirect MALDI-MS, as well as analysis by capillary electrophoresis. By comparing protein samples from healthy individuals with those from ill individuals, this method is suitable for establishing new, previously unknown mutations and quantifying the expression and incorporation of wild type to mutant.
Career Highlights
Brenner is associated with Pharis Biotec GmbH, where he applies his expertise in genetic diagnostics. His work has been instrumental in advancing the understanding of genetic mutations and their implications for human health.
Collaborations
Brenner has collaborated with notable professionals in his field, including Wolf-Georg Forssmann and Manfred Raida. These collaborations have further enriched his research and contributed to the development of innovative diagnostic methods.
Conclusion
Bernhard Brenner's contributions to genetic diagnostics exemplify the impact of innovation in the medical field. His patented method for detecting pathogenic mutations represents a significant advancement in the ability to diagnose genetic conditions effectively.