Bernd Kriekemeyer

Title: Innovations by Bernd Kriekemeyer – A Pioneer in Collagen-Binding Protein Research

Introduction

Bernd Kriekemeyer, located in Ulm, Germany, is a notable inventor in the field of biotechnology, specifically known for his contributions to collagen-binding proteins derived from enterococcal bacteria. With a portfolio of two patents, Kriekemeyer is instrumental in advancing methods that can prevent and treat enterococcal infections.

Latest Patents

Bernd Kriekemeyer's latest patents focus on a collagen-binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules) known as Ace, which is derived from enterococcal bacteria. This innovative protein is homologous to the ligand-binding region of Cna, another collagen-binding MSCRAMM. The Ace protein plays a crucial role in inhibiting the adhesion of enterococcal bacteria to extracellular matrix proteins. Notably, the N-terminal region of Ace contains a unique A domain, characterized by several 47-residue tandem repeat units, which underscores its potential utility in therapeutic applications. The patents outline methods for using Ace as well as antibodies raised against it to effectively inhibit the adhesion of enterococcal cells to collagen substrates, thus providing a means of preventing and treating infections caused by these bacteria.

Career Highlights

Throughout his career, Bernd Kriekemeyer has associated himself with prominent academic institutions such as the Texas A&M University System and the University of Texas System. His work has been recognized for its significant contributions to understanding bacterial adherence mechanisms, paving the way for innovative medical treatments.

Collaborations

In his research endeavors, Kriekemeyer has collaborated with notable colleagues, including Rebecca L. Rich and Rick T. Owens. These collaborations have fostered a dynamic exchange of ideas and have enhanced the impact of his research within the scientific community.

Conclusion

Bernd Kriekemeyer stands out as a pioneering inventor in the biotechnology realm, particularly in the area of collagen-binding proteins. His innovative patents, particularly the development of the Ace protein, provide promising avenues for combating enterococcal infections. Through his collaborations and career achievements, Kriekemeyer continues to make strides that could lead to substantial advancements in medical science.