Bernd Eikmanns

Title: Bernd Eikmanns: Innovations in Microbial Production of Amino Acids

Introduction

Bernd Eikmanns is a prominent German inventor based in Ulm, recognized for his significant contributions to biotechnology, particularly in the field of microbial production. With a total of three patents to his name, Eikmanns has made strides in enhancing amino acid production through innovative genetic methodologies.

Latest Patents

One of Bernd Eikmanns' latest patents involves the discovery of a nucleic acid encoding pyruvate carboxylase from coryneform glutamicum. This invention discloses a pyruvate carboxylase gene with SEQ ID NO:1, alongside an amino acid sequence defined by SEQ ID NO:2, which is expressed by the aforementioned gene. Moreover, the patent outlines a method for the microbial production of amino acids within the aspartate and/or glutamate family. This is accomplished by increasing the pyruvate carboxylase activity through genetic modification of the pyruvate carboxylase gene, followed by expression in a microorganism that synthesizes the corresponding amino acid indicated by SEQ ID NO:2.

Another notable patent covers a process for the fermentative preparation of L-amino acids utilizing coryneform bacteria. This methodology enhances the production capabilities by amplifying and overexpressing the subunit that contains the biotin-carboxyl carrier protein domain and the biotin-carboxylase domain of the nucleotide sequence encoding the enzyme acetyl-CoA carboxylase (accBC gene).

Career Highlights

Throughout his career, Bernd Eikmanns has been associated with reputable organizations dedicated to research and development. He has worked with Forschungszentrum Jülich GmbH, a leading research center specializing in various scientific fields, and Degussa Aktiengesellschaft, known for its expertise in specialty chemicals and innovative solutions.

Collaborations

During his professional journey, Eikmanns has collaborated with notable coworkers such as Hermann Sahm and Yvonne Tilg. Their combined efforts have contributed to advancements in biotechnological processes, particularly in the production of valuable biochemical compounds.

Conclusion

Bernd Eikmanns continues to push the boundaries of innovation in microbial biotechnology. His patents reflect a commitment to enhancing amino acid production through genetic engineering, emphasizing the importance of collaboration and research in driving technological advancements. As a leading inventor in his field, Eikmanns' work remains influential in the ongoing evolution of biotechnological applications.