This inventor holds 1 USPTO granted patent. Top assignee: Scripps Research Institute. Active years: 2022.
Company Filing History:
Years Active: 2022
Title: Bernard Kok: Innovator in Therapeutic Compounds
Introduction
Bernard Kok is a notable inventor based in La Jolla, California. He has made significant contributions to the field of therapeutic compounds, particularly in the area of proteostasis and the unfolded protein response.
Latest Patents
Kok holds a patent for "IRE1 activating compounds for use in therapy." This patent discloses compounds, their pharmaceutical salts, and pharmaceutical compositions that selectively activate the inositol-requiring enzyme 1 (IRE1)/X-box binding protein 1 (XBP1s) signaling pathway of the unfolded protein response (UPR). Importantly, these compounds do not target the IRE1 kinase domain. They are useful in treating diseases or conditions characterized by imbalances in proteostasis within the endoplasmic reticulum (ER) or secretory pathway, including those not associated with ER stress or activation of UPR. Kok has 1 patent to his name.
Career Highlights
Bernard Kok is affiliated with the Scripps Research Institute, where he continues to advance his research and innovation in therapeutic compounds. His work is pivotal in addressing critical health issues related to protein misfolding and cellular stress responses.
Collaborations
Kok collaborates with esteemed colleagues, including Aparajita Madhavan and Lars Plate, who contribute to his research endeavors and enhance the impact of his work.
Conclusion
Bernard Kok's innovative work in developing IRE1 activating compounds showcases his commitment to advancing therapeutic solutions for complex diseases. His contributions are vital in the ongoing quest to improve health outcomes through scientific innovation.