Irvine, CA, United States of America

Bernard H Choi

USPTO Granted Patents = 8 

Average Co-Inventor Count = 3.9

ph-index = 3

Forward Citations = 73(Granted Patents)


Location History:

  • Huntington Beach, CA (US) (2008)
  • Elk Grove, IL (US) (2022)
  • Irvine, CA (US) (2013 - 2023)

Company Filing History:


Years Active: 2008-2025

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8 patents (USPTO):Explore Patents

Title: Innovator Bernard H Choi: Advancements in Neurological Recovery Post-Cardiac Arrest

Introduction

Bernard H Choi is a notable inventor based in Irvine, CA, recognized for his contributions to the fields of neurology and emergency medicine. With an impressive portfolio of 8 patents, his innovative work focuses on enhancing outcomes for patients suffering from neurological injuries, particularly following cardiac arrest.

Latest Patents

One of Choi's latest patents addresses "Spreading depolarization and repolarization as biomarkers of neurological recovery after cardiac arrest." This pioneering work identifies an inverse correlation between the timing of a cortical spreading depolarization (SD) wave and neurological outcomes tested at 24 hours post-cardiopulmonary resuscitation (CPR). By quantifying features of SD and the newly identified 'repolarization (RP) wave', Choi's research offers crucial insights for diagnosing and prognosticating neurological injury related to hypoxia-ischemia. The findings present a potential for novel therapeutic interventions aimed at improving neurological recovery after such insults.

Additionally, Choi has developed a system for "Real-time methods to enable precision-guided CPR to improve neurological outcome and predict brain damage after ischemic injury and reperfusion." This innovation involves a multimodal optical imaging platform that assesses cerebral perfusion and metabolism to provide real-time feedback during CPR. By delivering light of various wavelengths to the tissue and analyzing the data captured, this method can quickly inform medical personnel about blood flow, oxygenation, and the overall conditions necessary to optimize patient recovery during acute brain injuries.

Career Highlights

As a distinguished member of the University of California, Choi has made significant contributions to medical research. His work not only improves clinical practices surrounding cardiac arrest but also enhances understanding of brain recovery mechanisms post-injury.

Collaborations

Choi collaborates with esteemed colleagues, including Christian Crouzet and Bruce J Tromberg. Together, they work towards advancing techniques and technologies aimed at better patient outcomes in critical situations.

Conclusion

Bernard H Choi's innovative contributions mark him as a significant figure in the realm of neurology and emergency medicine. His pioneering patents reflect his commitment to improving patient care and outcomes, particularly for those experiencing neurological injuries. Through collaboration and research, he continues to push the boundaries of medical knowledge and technology, paving the way for improved therapeutic approaches.

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