Company Filing History:
Years Active: 2013-2015
Title: The Innovations of Benjamin J. Gross: Pioneering Glycosylation Research in Philadelphia
Introduction
Benjamin J. Gross, based in Philadelphia, PA, is a notable inventor whose work has significantly advanced the field of glycosylation research. With a total of three patents to his name, Gross focuses on developing innovative methods and compositions that aim to address various glycosylation-associated disorders, such as diabetes and neurodegeneration.
Latest Patents
Gross's latest patents include transformative inventions that emphasize the modulation of protein glycosylation. One of his significant inventions, "Methods and compositions for detecting and modulating O-glycosylation," is instrumental in identifying therapeutic compounds for treating glycosylation-associated disorders. This invention targets diseases like neurodegeneration and diabetes, along with associated complications such as insulin resistance, nephropathy, and endothelial dysfunction. Furthermore, it also includes assays for discovering and testing candidate compounds aimed at regulating protein glycosylation.
Additionally, Gross has developed an invention that provides inhibitors of O-GlcNAc transferase, specifically using quinolinone-6-sulfonamides. This invention includes pharmaceutical compositions and methods applicable in the treatment of diabetes and its complications, neurodegenerative diseases, cancers, autoimmune diseases, and inflammatory diseases.
Career Highlights
Benjamin J. Gross contributes his expertise to Harvard College, where he engages in groundbreaking research in the biological sciences. His career is marked by his commitment to addressing critical healthcare issues through scientific innovation.
Collaborations
Throughout his career, Gross has collaborated with esteemed colleagues, including Suzanne Walker Kahne and Jonathan G. Swoboda. These partnerships have fostered a rich environment for innovation and discovery within the realm of glycosylation research.
Conclusion
Benjamin J. Gross exemplifies the spirit of innovation through his dedicated research and development efforts in glycosylation. His contributions have the potential to significantly impact therapeutic strategies for various diseases, reinforcing his role as a visionary inventor in the scientific community.