Behrouz Bruce Forood

Title: The Innovations of Behrouz Bruce Forood

Introduction

Behrouz Bruce Forood is a notable inventor based in San Diego, California. He has made significant contributions to the field of biotechnology, particularly in the development of polypeptide modifications. With a total of three patents to his name, Forood's work has advanced the understanding and application of chemical processes in biological systems.

Latest Patents

One of Forood's latest patents focuses on the C-terminal amidation of polypeptides. This patent provides compounds and methods for amidating the C-terminus of a polypeptide. The methods involve reacting a polypeptide that includes a C-terminal thioester or selenoester with a defined set of auxiliary molecules. This reaction produces a polypeptide adduct that includes the auxiliary molecule chemically bound at the C-terminal. The auxiliary molecule can be a substituted or unsubstituted 2-phenyl-2-amino ethanethiol, a substituted or unsubstituted 2-phenyl-2-amino ethaneselenol, or a substituted xanthene. In a subsequent step, a portion of the auxiliary molecule is removed, leaving the amide nitrogen and forming a C-terminal free amide polypeptide.

Another significant patent involves 2-aminopyridine derivatives and combinatorial libraries thereof. This work further showcases Forood's innovative approach to chemical compounds and their applications in various fields.

Career Highlights

Throughout his career, Forood has worked with several prominent companies, including Lion Bioscience AG and Amylin Pharmaceuticals, Inc. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in biotechnology.

Collaborations

Forood has collaborated with notable professionals in his field, including Brenton Todd Flatt and Christophe Chassaing. These collaborations have enriched his work and expanded the impact of his inventions.

Conclusion

Behrouz Bruce Forood is a distinguished inventor whose work in polypeptide modification and chemical processes has made a significant impact in biotechnology. His patents reflect a commitment to innovation and advancement in the field.