Bee Luan Khoo

Title: Innovations in Liquid Biopsy Detection by Bee Luan Khoo

Introduction

Bee Luan Khoo is an innovative inventor based in Singapore, known for her groundbreaking work in the field of medical diagnostics. She has made significant contributions to the detection of leukemia through her patented invention, which utilizes advanced microfluidics technology. Her work aims to improve the accuracy and efficiency of leukemia monitoring, particularly in early-stage patients.

Latest Patents

Khoo holds a patent for a technique titled "Liquid biopsy detection of leukemia using closed-loop microfluidics." This invention describes a one-step method for the simultaneous label-free detection and concentration of blast cells from a blood sample. The closed-loop microfluidics system allows for the continuous removal of waste and non-target cells, generating concentrated samples of high purity without the need for specific targeting of proteins by antibodies. This technique is particularly effective for samples that cannot be purified in a single run. The application of this invention demonstrates its potential for detecting rare blast cells, which is crucial for monitoring minimal residual disease in leukemia patients. The sensitivity of the invention enhances the detection of blast cells in blood samples from early-stage patients.

Career Highlights

Khoo is affiliated with the Massachusetts Institute of Technology, where she continues to advance her research in microfluidics and medical diagnostics. Her work has garnered attention for its innovative approach to solving complex medical challenges.

Collaborations

Some of her notable collaborators include Jongyoon Han and Kyungyong Choi, who have contributed to her research endeavors.

Conclusion

Bee Luan Khoo's contributions to the field of liquid biopsy detection represent a significant advancement in leukemia diagnostics. Her innovative techniques have the potential to improve patient outcomes and enhance the monitoring of this challenging disease.