This inventor holds 4 USPTO granted patents and 2 EPO patents. Top assignee: Other. Active years: 2019-2024.
Company Filing History:
3 out of 834,350 Years Active: 2019-2024
Title: Beatrix Wegemann: Innovator in Mass Spectrometry
Introduction
Beatrix Wegemann is a notable inventor based in Bremen, Germany. She has made significant contributions to the field of mass spectrometry, particularly in the preparation of biological cells for analysis. With a total of 4 patents, her work has advanced the understanding of cellular properties and their applications in various scientific fields.
Latest Patents
One of her latest patents focuses on the preparation of biological cells on mass spectrometric sample supports for desorbing ionization. This invention relates to the mass spectrometric analysis of cellular properties such as taxonomic classification, antibiotic resistances, and responses to drugs or other active substances. The cells involved can be either prokaryotic or eukaryotic microorganisms, cultivated directly on a mass spectrometric sample support, or eukaryotic cells derived from tissues or cell cultures. The innovative aspect of this invention is that the cells are not disrupted by adding a matrix solution for subsequent ionization through matrix-assisted laser desorption (MALDI). Instead, they are disrupted in a separate treatment step using acids and/or solvents on the sample support itself. This method allows the released cell proteins to adhere to the sample support, enabling careful washing with buffer solution to remove salts and other soluble impurities.
Career Highlights
Throughout her career, Beatrix Wegemann has worked with various companies, including Bruker Daltonik GmbH. Her expertise in mass spectrometry has positioned her as a key figure in the development of innovative techniques for biological analysis.
Collaborations
Beatrix has collaborated with notable professionals in her field, including her coworker Katrin Sparbier. Their joint efforts have contributed to advancements in mass spectrometric techniques and applications.
Conclusion
Beatrix Wegemann's contributions to mass spectrometry and her innovative patents have significantly impacted the analysis of biological cells. Her work continues to influence the scientific community and enhance our understanding of cellular properties.