The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
Apr. 04, 2016
Applicant:
Bruker Daltonik Gmbh, Bremen, DE;
Inventors:
Katrin Sparbier, Bremen, DE;
Beatrix Wegemann, Bremen, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); H01J 49/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); H01J 49/0418 (2013.01);
Abstract
The invention relates to methods and instruments for determining the resistances of microbes to antibiotics, in particular those microbes which produce beta-lactamases. The method determines the resistance of the microbes in less than an hour by incubating a tiny quantity of the microbes on a mass spectrometric sample support plate after they have been combined with a dosed quantity of a suitable antibiotic, for example the beta-lactam antibiotic imipenem, and by direct mass spectrometric measurement of the breakdown of the antibiotic by the microbial enzymes.