Company Filing History:
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Years Active: 1999-2010
Title: The Innovative Contributions of Barry J Byrne
Introduction
Barry J Byrne is a prominent inventor based in Baltimore, MD, known for his significant contributions to the field of gene therapy. With a total of 8 patents to his name, Byrne has focused on developing methods to treat anemia through innovative techniques involving recombinant adeno-associated virus (AAV) virions. His work has the potential to revolutionize the treatment of this condition, providing new avenues for patient care.
Latest Patents
Byrne's latest patents include groundbreaking methods for treating anemia using recombinant adeno-associated virus virions. One patent discloses the use of AAV virions for the delivery of DNA molecules to muscle cells and tissue. This invention allows for direct, in vivo injection of recombinant AAV virions into muscle tissue, such as through intramuscular injection. Additionally, it enables the in vitro transduction of muscle cells, which can then be introduced into a subject for treatment. The invention ensures sustained, high-level expression of a delivered nucleotide sequence encoding erythropoietin, facilitating in vivo secretion from transduced muscle cells for systemic delivery. Another patent focuses on similar methods for delivering DNA to muscle cells using AAV virions, emphasizing the sustained expression of therapeutic proteins.
Career Highlights
Throughout his career, Barry J Byrne has worked with notable organizations, including Avigen, Inc. and The Johns Hopkins University. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to significant advancements in gene therapy.
Collaborations
Byrne has collaborated with esteemed colleagues such as Gregory M Podsakoff and Paul D Kessler. These partnerships have further enhanced his research and development efforts, leading to innovative solutions in the treatment of anemia.
Conclusion
Barry J Byrne's work exemplifies the impact of innovation in medical science, particularly in the treatment of anemia through gene therapy. His patents and collaborations highlight his commitment to advancing healthcare solutions.