Location History:
- Cologne, DE (2009)
- Köln, DE (2010)
- Wuppertal, DE (2012 - 2015)
Company Filing History:
1 out of 1 
1 out of 1,777 
1 out of 22 
Years Active: 2009-2015
Title: Axel Bouchon: Innovator in Myeloid Cell Research
Introduction
Axel Bouchon is a prominent inventor based in Wuppertal, Germany. He has contributed significantly to the field of immunology with a focus on myeloid cells. With two patents to his name, Bouchon's work centers around novel activating receptors known as TREM (triggering receptor expressed on myeloid cells).
Latest Patents
Bouchon's latest patents detail the innovative use of TREM-1 and TREM-2, which are members of the Ig super-family expressed on human myeloid cells. TREM-1 is a transmembrane glycoprotein selectively found on blood neutrophils and a subset of monocytes, being upregulated by bacterial and fungal products. This receptor has promising applications in the treatment and diagnosis of various inflammatory diseases. On the other hand, TREM-2 is expressed on mast cells and peripheral dendritic cells. Stimulation of dendritic cells via TREM-2 is crucial for DC maturation, resistance to apoptosis, and promoting chemotaxis towards macrophage inflammatory protein 3-β. This indicates TREM-2's utility in modulating immune responses in autoimmune disorders and allergic conditions.
Career Highlights
Throughout his career, Axel Bouchon has worked with reputable companies such as Cosmo Research & Development S.p.A. and Novo Nordisk A/S. His expertise and innovative approach have led to significant advancements in the understanding of myeloid cell receptors.
Collaborations
Bouchon has collaborated with notable scientists in his field, including Marco Colonna and Rune Salbo. These partnerships have enhanced his research endeavors and contributed to the growth of knowledge regarding myeloid cell functions.
Conclusion
Axel Bouchon remains a key figure in immunology research, particularly in the study of myeloid cells and their receptors. His patents on TREM-1 and TREM-2 demonstrate his commitment to advancing medical science, with implications for diagnosing and treating various inflammatory and immune disorders. Through innovative research and effective collaborations, Bouchon continues to impact the scientific community positively.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.