Avram Goldstein

Title: Avram Goldstein: Innovator in MHC Class I Modulation

Introduction

Avram Goldstein, an accomplished inventor based in Stanford, California, has made significant contributions in the field of biomedical research. With a portfolio of 7 patents, his work focuses on the modulation of surface membrane receptors, particularly through mechanisms involving MHC Class I antigens. His innovative approaches hold the potential to impact therapeutic strategies in immunology and beyond.

Latest Patents

Goldstein's latest patents delve into the intricacies of Class I MHC modulation of surface receptor activity. One of his notable patents provides methods and compositions aimed at regulating surface membrane receptor responses by modulating the interaction between MHC Class I antigens and surface membrane receptors. His techniques either enhance or reduce this interaction through methods such as increasing surface expression of the MHC Class I antigen or utilizing agents that modify receptor interactions. Additionally, he explores the aggregative characteristics of oligopeptides that influence these interactions, proposing their use in screening assays to identify drugs that can affect MHC Class I antigen interactions. These active peptide characteristics may also offer innovative methods for administering agents that modulate surface receptor responses.

Career Highlights

Throughout his career, Avram Goldstein has collaborated with various esteemed institutions and companies, enhancing his expertise and research capabilities. Noteworthy among these are the Syva Company and the University of California, where he has contributed to groundbreaking research and development in the biomedical field.

Collaborations

Goldstein's innovative journey is marked by fruitful collaborations with notable colleagues such as Richard K. Leute and Edwin F. Ullman. These partnerships highlight the collaborative spirit essential in the realm of scientific discovery and innovation, fostering a dynamic environment for the development of new technologies.

Conclusion

Avram Goldstein remains a pivotal figure in the realm of invention and innovation, particularly in the modulation of membrane receptors relevant to immune responses. His extensive patent portfolio reflects a commitment to advancing biomedical research through creative solutions and collaborative efforts. Goldstein's contributions not only demonstrate the importance of scientific inquiry but also pave the way for future advancements in therapeutic modalities.