August Wilhelm Wahlefeld

Title: August Wilhelm Wahlefeld: Innovator in Analytical Chemistry

Introduction

August Wilhelm Wahlefeld is a notable inventor based in Weilheim, Germany. He has made significant contributions to the field of analytical chemistry, particularly through his innovative patents. With a total of four patents to his name, Wahlefeld has developed methods that enhance the accuracy and efficiency of enzymatic determinations in biological fluids.

Latest Patents

Wahlefeld's latest patents include the development of gamma-Glutamyl-4-nitroanilide compounds. These compounds are utilized to determine gamma-glutamyl-transpeptidase activity by contacting a sample suspected of containing the enzyme with the compound and glycylglycine. The liberation of the resulting p-nitro-aniline compound serves as a measure of the enzyme's activity present in the sample. Another significant patent involves an analytical process for the enzymatic determination of a substrate in biological fluids. This method allows for accurate measurement of NADH consumption after separating the enzymes from the reaction solution, making it economical and efficient.

Career Highlights

Wahlefeld has been associated with Boehringer Mannheim GmbH, where he has applied his expertise in analytical chemistry. His work has led to advancements in the methodologies used for enzyme analysis, contributing to the field's overall progress.

Collaborations

Wahlefeld has collaborated with notable coworkers such as Erich Bernt and Wolfgang Gruber. Their combined efforts have furthered the development of innovative solutions in analytical chemistry.

Conclusion

August Wilhelm Wahlefeld's contributions to analytical chemistry through his patents and collaborations have significantly impacted the field. His innovative approaches continue to influence the methodologies used in enzyme analysis today.