Location History:
- Hohenpeissenberg, DE (1987 - 1989)
- HohenpeiBenberg, DE (1990)
- Weilheim, DE (1979 - 1992)
Company Filing History:
Years Active: 1979-1992
Title: **August W. Wahlefeld: A Pioneer in Enzymatic Analysis**
Introduction
August W. Wahlefeld, an esteemed inventor based in Weilheim, Germany, has made significant contributions to the field of enzymatic analysis. With an impressive portfolio of 11 patents, Wahlefeld's innovative work primarily focuses on the determination of alpha-amylase and the preparation of specialized substrates.
Latest Patents
One of his latest inventions involves a process for preparing a maltoheptaose derivative, where alpha-amylase activity is determined through the enzymatic splitting of an alpha-amylase substrate. This process utilizes a maltoheptaose compound with a glucoside or sugar moiety, allowing the measurement of the fission products generated. Another remarkable patent is dedicated to the development of monoclonal antibodies for the specific determination of pancreatic alpha-amylase in body fluids, utilizing a binding system that minimizes cross-reactivity with saliva alpha-amylase.
Career Highlights
Wahlefeld's prolific career is underscored by his affiliations with Boehringer Mannheim GmbH, where he has played a vital role in advancing enzymatic testing technologies. His work has not only refined methods of surface-level enzyme assays but has also enabled significant improvements in clinical diagnostics and research applications.
Collaborations
Throughout his career, Wahlefeld has collaborated with notable colleagues, including Wolfgang Gruber and Elli Rauscher. These partnerships have fostered a collaborative spirit that has propelled innovative research and development in their field.
Conclusion
August W. Wahlefeld's dedication to enzymatic analysis and his impactful patents reflect his vital role in the scientific community. His innovations continue to influence the landscape of clinical testing, showcasing the importance of creativity and collaboration in scientific advancement. His legacy is marked by a commitment to enhancing diagnostic methodologies and contributing to the health sciences.
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