Company Filing History:
Years Active: 2017-2020
Title: The Innovative Contributions of Audrey Nommay
Introduction
Audrey Nommay is a prominent inventor based in Blotzheim, France. She has made significant contributions to the field of biotechnology, particularly in the development of methods for selecting mammalian host cells that express polypeptides of interest with high yield. With a total of two patents to her name, her work has the potential to impact various applications in medicine and research.
Latest Patents
Audrey Nommay's latest patents focus on the cell surface display of polypeptide isoforms by stop codon readthrough. The first patent describes a method for selecting mammalian host cells that express a polypeptide of interest with high yield. The host cells contain an expression cassette that includes a first polynucleotide encoding the polypeptide of interest, at least one leaky stop codon downstream of the first polynucleotide, and a second polynucleotide encoding an immunoglobulin transmembrane anchor. This innovative approach allows for the expression of the polypeptide of interest as a fusion polypeptide displayed on the cell surface, enabling the selection of high-expressing host cells based on the presence or amount of the displayed fusion polypeptide.
The second patent elaborates on a similar method, emphasizing the cultivation of host cells to express polypeptides as fusion proteins displayed on the cell surface. This method also involves selecting high-producing cells based on the presence or amount of the displayed fusion polypeptides, further enhancing the efficiency of polypeptide production.
Career Highlights
Audrey Nommay is currently employed at Novartis AG, a leading global healthcare company. Her work at Novartis allows her to collaborate with other experts in the field and contribute to groundbreaking research and development in biotechnology.
Collaborations
Some of her notable coworkers include Thomas Jostock and Hans-Peter Knopf. Their collaboration fosters an environment of innovation and shared expertise, which is essential for advancing their research initiatives.
Conclusion
Audrey Nommay's contributions to biotechnology through her innovative patents and collaborations highlight her role as a significant inventor in her field. Her work continues to pave the way for advancements in the production of therapeutic proteins and other biotechnological applications.