Atsushi Ohta

Title: Innovations of Atsushi Ohta

Introduction

Atsushi Ohta is a prominent inventor based in Kanagawa, Japan. He has made significant contributions to the field of peptide chemistry, holding a total of 21 patents. His work focuses on developing novel methods for drug discovery and peptide synthesis.

Latest Patents

One of his latest patents is a peptide-compound cyclization method. The objective of this invention is to provide methods for discovering drugs that are effective for challenging targets, which have traditionally been difficult to identify. This invention relates to innovative methods for cyclizing peptide compounds, as well as novel peptide compounds and libraries that comprise these compounds. Another significant patent is a method for synthesizing peptides in a cell-free translation system. This invention aims to synthesize peptides containing structurally diverse amino acids using cell-free translation systems, achieving superior translational efficiency compared to conventional techniques. The method involves protecting an amino acid linked to tRNA with an appropriate protecting group and performing the deprotection and peptide translation steps in parallel.

Career Highlights

Atsushi Ohta has worked with notable companies such as Nippon Telegraph and Telephone Corporation and Chugai Pharmaceutical Co., Ltd. His experience in these organizations has contributed to his expertise in peptide chemistry and drug discovery.

Collaborations

He has collaborated with esteemed colleagues, including Tomoaki Kumagai and Shinya Otsuki. Their joint efforts have further advanced the field of peptide research.

Conclusion

Atsushi Ohta's innovative work in peptide chemistry and drug discovery has led to significant advancements in the field. His contributions through various patents demonstrate his commitment to improving methods for synthesizing peptides and discovering effective drugs.