Arthur P Bode

Title: Innovations of Arthur P. Bode in Blood Cell Technology

Introduction

Arthur P. Bode is a notable inventor based in Greenville, NC (US), recognized for his significant contributions to the field of blood cell technology. He holds a total of seven patents, showcasing his innovative approach to medical science and blood preservation.

Latest Patents

Among his latest patents, Bode has developed fixed-dried red blood cells (RBCs) and processes for preparing them. These RBCs, when reconstituted with distilled water or an appropriate buffer, exhibit the ability to bind oxygen with native affinities, possess partial deformability, and present minimal thrombogenicity to platelets. The red blood cells are preferably fixed using cross-linkers with aldehyde functions, such as paraformaldehyde or glutaraldehyde, either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Additionally, blood group antigens and chemical functions that could render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are ideally dried by lyophilization.

Career Highlights

Bode has had a distinguished career, working with esteemed institutions such as the University of North Carolina at Chapel Hill and East Carolina University. His work has significantly advanced the understanding and application of blood cell technology.

Collaborations

Throughout his career, Bode has collaborated with notable colleagues, including Marjorie S. Read and Robert L. Reddick. These partnerships have contributed to the development of innovative solutions in the field.

Conclusion

Arthur P. Bode's contributions to the field of blood cell technology through his patents and collaborations highlight his role as a leading inventor. His work continues to influence advancements in medical science and blood preservation techniques.