Company Filing History:
Years Active: 2025
Title: Arthur Henry Antoon Marie Van Onzen: Innovator in Bio-Orthogonal Drug Activation
Introduction
Arthur Henry Antoon Marie Van Onzen is a notable inventor based in Nijmegen, Netherlands. He has made significant contributions to the field of bio-orthogonal drug activation, showcasing his innovative spirit and dedication to advancing medical science.
Latest Patents
Van Onzen holds a patent for a "Cleavable tetrazine used in bio-orthogonal drug activation." This invention represents an advancement in provoked chemical cleavage. The invention provides the use of a diene as a chemically cleavable group attached to a Construct. It also involves the use of a dienophile to provoke the release of the Construct by allowing the diene to react with a dienophile capable of undergoing an inverse electron demand Diels Alder reaction with the diene. The invention includes a kit for releasing a Construct Cbound to a Trigger T, where the kit contains a tetrazine and a dienophile, with the Trigger being the tetrazine. Additionally, the invention includes the formation of a pyridazine by reacting a tetrazine having a Construct Cbound thereto and a dienophile, serving as a chemical tool for the release of the Construct in a chemical, biological, or physiological environment.
Career Highlights
Van Onzen is currently associated with Tagworks Pharmaceuticals B.V., where he continues to work on innovative solutions in drug activation. His expertise and contributions have positioned him as a valuable asset in the pharmaceutical industry.
Collaborations
He has collaborated with notable colleagues, including Marc Stefan Robillard and Wolter Ten Hoeve, further enhancing the innovative environment at Tagworks Pharmaceuticals B.V.
Conclusion
Arthur Henry Antoon Marie Van Onzen exemplifies the spirit of innovation in the pharmaceutical field through his groundbreaking work on bio-orthogonal drug activation. His contributions are paving the way for advancements in medical treatments and drug delivery systems.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.