This inventor holds 2 USPTO granted patents. Top assignee: Ramot University Authority for Applied Research and Industrial Development Limited. Active years: 2003-2005.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2003-2005
Title: The Innovative Contributions of Arnold Simons
Introduction
Arnold Simons is a notable inventor based in Carcur, Illinois. He has made significant contributions to the field of genetic screening, holding a total of 2 patents. His work focuses on methods that leverage synthetic lethality to advance our understanding of gene functions.
Latest Patents
Simons' latest patents include groundbreaking methods for genetic screening. One patent describes a method for screening molecules that exhibit synthetic lethal properties when combined with a gene of interest carrying a non-lethal mutation. This method involves transfecting a first reporter gene into mammalian cells, selecting clones that stably express the reporter gene, and introducing a survival plasmid that contains a functioning copy of the gene of interest. The process culminates in identifying molecules that can impose selective pressure, thereby revealing their synthetic lethal properties.
Another patent outlines a screening method that applies the principle of synthetic lethality to non-yeast eukaryotic cells. This method can be utilized to screen chemical libraries or DNA molecules to identify modulators of gene function that are synergistically lethal when paired with an incapacitated gene of interest. The patent also describes episomal survival plasmids and kits that facilitate this innovative screening process.
Career Highlights
Arnold Simons is affiliated with Ramot University Authority for Applied Research and Industrial Development Limited. His work at this institution has allowed him to explore and develop advanced genetic screening techniques that have the potential to impact various fields, including medicine and biotechnology.
Collaborations
Simons has collaborated with esteemed colleagues such as Dan Canaani and Naomi Dafni. These partnerships have likely contributed to the depth and breadth of his research, fostering an environment of innovation and discovery.
Conclusion
Arnold Simons is a distinguished inventor whose work in genetic screening methods showcases his innovative spirit and dedication to advancing scientific knowledge. His contributions are poised to make a lasting impact in the field of genetics and beyond.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile