Arjun Raj

Title: Arjun Raj: Innovator in Genetic Detection Technologies

Introduction

Arjun Raj is a prominent inventor based in Wynnewood, PA (US). He has made significant contributions to the field of genetic detection technologies, holding a total of 3 patents. His work focuses on innovative methods for analyzing genetic material at the single-cell level, which has important implications for research and medical diagnostics.

Latest Patents

One of Arjun Raj's latest patents is a "Method for detecting mutations in single cells or single molecules." This invention provides a high-efficiency fluorescence in situ hybridization (FISH) method for detecting mutations on individual RNA transcripts, including both exonic and intronic RNA transcripts. In certain embodiments, the method is used to quantify allelic expression at the population and single-cell level, and also to distinguish maternal chromosomes from paternal chromosomes in single cells.

Another significant patent is the "Method for detecting chromosome structure and gene expression simultaneously in single cells." This invention relates to systems and methods for measuring chromosome structure and gene expression. In one embodiment, it includes an assay for determining the spatial organization of gene expression in the nucleus. The method based on fluorescence in situ hybridization (FISH) simultaneously yields information on the physical position and expression of individual genes. By lighting up a large number of targets on a particular chromosome using a bar-coding scheme, the large-scale structure of an entire chromosome can be determined.

Career Highlights

Arjun Raj has worked at prestigious institutions such as the University of Pennsylvania and Rutgers, The State University of New Jersey. His experience in these research environments has allowed him to develop and refine his innovative techniques in genetic analysis.

Collaborations

Throughout his career, Arjun Raj has collaborated with notable colleagues, including Marshall J Levesque and Sanjay Tyagi. These collaborations have further enhanced his research and contributed to the advancement of genetic detection technologies.

Conclusion

Arjun Raj is a leading inventor whose work in genetic detection technologies has the potential to revolutionize the field. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and improving diagnostic methods.