Aristides Tagalakis

Title: Aristides Tagalakis and Mucus-Translocating Nanoparticle Innovation.

Introduction

Aristides Tagalakis is an inventor associated with Liverpool, Great Britain, and the pharmaceutical company Algipharma AS. His patent work addresses a challenge in drug delivery: helping micro- and nanoparticles cross mucus layers.

Latest Patents

Tagalakis is associated with 1 patent, titled “Use of alginate oligomers to enhance the translocation of micro/nanoparticles across mucus layers.” The invention describes methods for moving cationic micro- or nanoparticles across mucus by using alginate oligomers containing at least 70% mannuronate residues. The oligomers may be applied alongside the particles or used to coat them before they contact the mucus layer.

The patent also describes a method for transporting a molecule of interest across mucus in a self-assembling micro- or nanoparticle. The particle includes a cationic particle-forming agent and a qualifying alginate oligomer, and may carry the molecule of interest, which can optionally be covalently bound to one or more particle components.

Career Highlights

The patent reflects Tagalakis’s work on particle-based delivery approaches that may help transport molecules through mucus barriers. His company affiliation is Algipharma AS.

Collaborations

The provided information identifies Stephen Hart and Are Kristiansen as Tagalakis’s coworkers. Their specific roles in the patent or related research are not specified.

Conclusion

Aristides Tagalakis’s patent focuses on using mannuronate-rich alginate oligomers to support the movement of micro- and nanoparticles, and their molecular cargo, across mucus layers.