Schwenksville, PA, United States of America

Aquiles E Leyes

This inventor holds 2 USPTO granted patents. Top assignee: Merck Sharp + Dohme Corp.. Active years: 2010-2012.


Average Co-Inventor Count = 1.6

ph-index = 1


Company Filing History:


Years Active: 2010-2012

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2 patents (USPTO):Explore Patents

Title: Aquiles E Leyes: Innovator in Antidiabetic Compounds

Introduction

Aquiles E Leyes is a notable inventor based in Schwenksville, PA (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of antidiabetic compounds. With a total of 2 patents, his work focuses on innovative crystalline forms that enhance the efficacy of treatments for type 2 diabetes and related conditions.

Latest Patents

Leyes' latest patents include a novel crystalline salt form of an antidiabetic compound. This crystalline anhydrous toluenesulfonic acid salt form of a selective PPAR gamma partial agonist is characterized by its stability and non-hygroscopic properties. It is particularly useful for creating pharmaceutical formulations aimed at treating type 2 diabetes, hyperglycemia, obesity, and dyslipidemia. Another significant patent involves novel crystalline forms of two indole compounds linked to phenoxyalkylcarboxylic acid groups. These compounds serve as selective PPAR gamma partial agonists and are beneficial in treating type 2 diabetes, hyperglycemia, obesity, dyslipidemia, and metabolic syndrome. The invention encompasses various crystalline forms, including a crystalline free acid dihydrate and an anhydrate, along with pharmaceutical compositions and processes for their preparation.

Career Highlights

Aquiles E Leyes is currently associated with Merck Sharp & Dohme Corp., where he continues to advance his research in pharmaceutical innovations. His work has been instrumental in developing new therapeutic options for patients suffering from metabolic disorders.

Collaborations

Leyes has collaborated with esteemed colleagues such as Dalian Zhao and Jean-Francois Marcoux. These partnerships have fostered a collaborative environment that enhances the research and development of innovative pharmaceutical solutions.

Conclusion

Aquiles E Leyes stands out as a prominent inventor in the pharmaceutical industry, particularly in the realm of antidiabetic treatments. His innovative patents and collaborations contribute significantly to advancements in healthcare.

Profile summary based on public USPTO records.
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