Ao Chen

Title: Innovations of Ao Chen in Quinazoline Derivatives

Introduction

Ao Chen is a notable inventor based in Shanghai, China. He has made significant contributions to the field of chemistry, particularly in the development of quinazoline derivatives. His work focuses on improving the properties of these compounds, which have various applications in pharmaceuticals.

Latest Patents

Ao Chen holds a patent for a salt of a quinazoline derivative, specifically N-[4-(3-chlorine-4-fluoroanilino)]-7-(3-morpholinepropanol)-6-(2-fluoroacrylamide)-quinazoline. This innovative compound exhibits improved properties compared to known quinazoline derivatives, particularly in terms of water solubility. The patent highlights that the salt forms, including citrate, benzene sulfonate, and ethanedisulphonate, demonstrate enhanced crystallinity and reduced moisture absorption.

Career Highlights

Ao Chen is currently employed at Shanghai Pharmaceuticals Holding Co., Ltd. His work at this leading pharmaceutical company allows him to apply his expertise in developing new chemical compounds that can lead to advancements in drug formulation and delivery.

Collaborations

Ao Chen collaborates with talented colleagues, including Guangxin Xia and Di Li. Their combined efforts contribute to the innovative research and development initiatives at Shanghai Pharmaceuticals.

Conclusion

Ao Chen's contributions to the field of quinazoline derivatives exemplify the importance of innovation in pharmaceutical chemistry. His patented work not only enhances the properties of these compounds but also paves the way for future advancements in drug development.