Company Filing History:
Years Active: 1991-1996
Title: Antonio Mele: Innovator in Biotechnology
Introduction
Antonio Mele is a prominent inventor based in Pavia, Italy. He has made significant contributions to the field of biotechnology, particularly in the development of plasmid vectors for protein expression. With a total of 3 patents to his name, Mele's work has implications in pharmaceuticals and food production.
Latest Patents
One of his latest patents is the PSM112 plasmid vector for expression in Bacillus subtilis. This plasmid vector is utilized for cloning heterologous proteins in Bacillus subtilis. The method of constructing plasmid pSM112 involves several steps, including linearization of plasmid pSM23 with the XbaI restriction enzyme, cyclization with T4 DNA ligase, and isolation of the plasmid pSM112. Additionally, he has developed a cloning vector that facilitates the expression and secretion of heterologous proteins in Bacillus subtilis. This vector allows for the creation of recombinant DNA molecules, which can be transformed into Bacillus subtilis cells, enabling high yields of the desired proteins.
Career Highlights
Antonio Mele is currently associated with Eniricerche S.p.a., where he continues to innovate in the field of biotechnology. His work focuses on the development of cloning vectors and recombinant DNA technologies that have practical applications in various industries.
Collaborations
Mele has collaborated with notable colleagues such as Guido Grandi and Salvatore Toma. These collaborations have further enhanced his research and development efforts in biotechnology.
Conclusion
Antonio Mele's contributions to the field of biotechnology through his innovative patents and collaborations highlight his role as a key inventor in the industry. His work continues to impact the production of pharmaceuticals and food substances, showcasing the importance of biotechnology in modern science.