Company Filing History:
1 out of 4 
1 out of 26 
1 out of 4 Years Active: 2001-2006
Title: Innovations by Antonio Facchiano in Prosthetic and Growth Factor Technologies
Introduction
Antonio Facchiano, a prominent inventor based in Rome, Italy, has made significant contributions to the fields of prosthetics and cellular biology. With a total of five patents to his name, he continues to push the boundaries of medical technology and innovation.
Latest Patents
Facchiano's latest patents showcase his focus on improving prosthetic devices and cellular interactions. One notable invention is an advanced prosthetic graft designed for bypassing, replacing, or repairing vessels and organs in contact with blood flow. This unique graft features a porous implant with adherent cells on its outer surface, which are genetically modified to express proteins that enhance graft patency. This innovation has demonstrated a long-term success rate that surpasses other existing solutions.
Another significant patent involves a novel peptide that inhibits the activity of Platelet-Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF). Derived from the human fibroblast growth factor, this peptide can effectively block the effects of these growth factors on rat smooth muscle cells and bovine endothelial cells in vitro, while also showing potential in inhibiting angiogenesis in live CD1 mice.
Career Highlights
Throughout his career, Antonio Facchiano has worked with notable companies in the medical field, including Sulzer Biologics, Inc. and Zimmer Orthobiologics, Inc. His experiences in these organizations have contributed to the development of his innovative technologies and have established him as a leading figure in medical inventions.
Collaborations
Facchiano's work has been enriched through collaborations with esteemed colleagues, notably Diane Lee Anderson and John Paul Ranieri. Their combined efforts have fostered an innovative environment, leading to breakthroughs in the design and application of medical technologies.
Conclusion
Antonio Facchiano stands out as an influential inventor whose work in prosthetic grafts and peptide development has significantly advanced medical science. With a focus on improving patient outcomes and a commitment to innovation, his inventions are set to influence the future of medical treatments and technologies.