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Years Active: 2005-2007
Title: Annie Yang: Innovator in Cell Regulatory Genes
Introduction
Annie Yang is a prominent inventor based in Boston, MA (US). She has made significant contributions to the field of genetics, particularly in the study of cell regulatory genes. With a total of 3 patents to her name, her work has implications for understanding tumor suppressor genes and their functions.
Latest Patents
Annie Yang's latest patents focus on the cloning of p63, a gene located at chromosome 3q27-29, which shares homology with the tumor suppressor p53. This application describes how the p63 gene encodes at least six different isotypes. Notably, p63 has been detected in various human and mouse tissues, demonstrating remarkably divergent activities. These include the ability to transactivate p53 reporter genes and induce apoptosis. Furthermore, isotopes of p63 that lack a transactivation domain act as dominant negatives towards the transactivation by both p53 and p63.
Career Highlights
Throughout her career, Annie Yang has worked with esteemed institutions such as Harvard College and Brigham and Women's Hospital, Inc. Her research has significantly advanced the understanding of cell regulatory mechanisms and their potential applications in medicine.
Collaborations
Annie has collaborated with notable colleagues in her field, including Frank McKeon and Massimo Loda. Their joint efforts have contributed to the advancement of research in cell biology and genetics.
Conclusion
Annie Yang's innovative work in the field of cell regulatory genes has established her as a key figure in genetic research. Her contributions continue to influence the understanding of tumor suppressor genes and their roles in cellular processes.