Company Filing History:
Years Active: 2011
Title: Annette Deufel: Innovator in Thermostable DNA Polymerase Technology
Introduction: Annette Deufel is a prominent inventor based in Munich, Germany, known for her significant contributions to biotechnology. With a focus on enhancing the efficiency of DNA polymerases, her work has impacted molecular biology research and applications particularly in the field of diagnostics.
Latest Patents: Annette Deufel holds a patent for a thermostable Taq polymerase fragment, specifically TaqΔ288. This invention highlights a fragment of native DNA polymerase (TaqWT) that is missing 288 N-terminal amino acids, exhibiting increased thermostability compared to its counterparts, TaqΔ279 and TaqΔ289. The patent encompasses recombinant expression vectors that encode TaqΔ288, purification protocols, and various kits incorporating her innovation. Furthermore, the invention details methods for sequencing nucleic acid templates and amplifying target nucleic acids.
Career Highlights: Deufel is associated with Roche Diagnostics Operations, Inc., a leading company in the diagnostics sector. Her work has advanced the understanding and utilization of DNA polymerases, which are crucial for numerous applications in genetic research and diagnostic testing.
Collaborations: Throughout her career, Annette has collaborated with esteemed colleagues, including Thomas Meier and Waltraud Ankenbauer. These collaborations have further propelled research and development in the biotechnology sphere, highlighting the importance of teamwork in innovation.
Conclusion: Annette Deufel's contributions to the field of biochemistry through her invention of the thermostable Taq polymerase fragment represent a noteworthy advancement in DNA technology. Her patent not only enhances the capabilities of scientific research but also showcases the pivotal role of innovative inventors in driving progress within the biotechnology industry.