This inventor holds 1 USPTO granted patent. Top assignee: Max-Delbruck-Centrum Fur Molekulare Medizin in Der Helmholtz-Gemeinschaft. Active years: 2025.
Company Filing History:
Years Active: 2025
Title: Anne Ast - Innovator in Protein Research
Introduction
Anne Ast is a prominent inventor based in Berlin, Germany. She has made significant contributions to the field of molecular medicine, particularly in understanding protein misfolding and its implications in diseases.
Latest Patents
Anne Ast holds a patent for a "Fret-based method to measure seeding activity of misfolded protein species in biological samples." This invention relates to a method for quantifying the seeding of amyloidogenic aggregates. It also includes methods for assessing the risk of developing, predicting the onset, or evaluating the progression of polyQ diseases. Furthermore, her patent outlines a method for identifying compounds that inhibit mHTT seeding activity in vitro. The invention utilizes fluorophore-bearing polyQ proteins, especially mutant N-terminal huntingtin fragments comprising exon-1 and related soluble protein constructs.
Career Highlights
Anne Ast is affiliated with the Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft. Her work focuses on innovative approaches to tackle complex biological challenges related to protein misfolding.
Collaborations
She collaborates with notable colleagues, including Alexander Buntru and Erich Wanker, to advance research in her field.
Conclusion
Anne Ast's contributions to protein research and her innovative patent highlight her role as a key figure in molecular medicine. Her work continues to pave the way for advancements in understanding and treating polyQ diseases.