Company Filing History:
Years Active: 2024
Title: The Innovative Journey of Anna Mallone in Bioengineering
Introduction: Anna Mallone, an accomplished inventor based in Schlieren, Switzerland, has made significant contributions to the field of bioengineering. With one patent to her name, she has developed an innovative method that focuses on creating an in vitro 3D model of human atherosclerotic plaque. Her work is crucial for advancing research in cardiovascular diseases.
Latest Patents: Mallone's notable patent, titled "Bioengineered in vitro 3D model of human atherosclerotic plaque," outlines a novel method for generating a layered cellular 3D microtissue aggregate. The process involves contacting myeloid cells with a protein kinase C agonist to yield primed myeloid cells. These cells are then incubated with low-density lipoprotein (LDL) in a confined volume, specifically through a hanging drop culture, which leads to the formation of a 3D culture of myeloid cells. Further incubation of this 3D culture with fibroblasts in the presence of LDL results in the formation of the layered cellular aggregate, a breakthrough for biomedical research.
Career Highlights: Anna Mallone is associated with the University of Zurich, where she applies her expertise in bioengineering to further her research. Her dedication to exploring innovative solutions in healthcare has made her a prominent figure within her field.
Collaborations: Throughout her career, Mallone has collaborated with esteemed colleagues like Simon Philipp Hoerstrup and Benedikt Weber. These partnerships highlight the importance of teamwork in driving innovation and addressing complex biomedical challenges.
Conclusion: Anna Mallone's inventive work in developing a 3D model of human atherosclerotic plaque demonstrates her commitment to advancing medical research. As she continues to innovate within the bioengineering field, her contributions are poised to have a lasting impact on cardiovascular disease understanding and treatment.