Aniko V Paul

Title: Aniko V Paul: Innovator in Oncolytic Virus Research

Introduction

Aniko V Paul is a prominent inventor based in Setauket, NY (US). She has made significant contributions to the field of virology, particularly in the development of novel therapies for cancer treatment. With a total of 4 patents, her work focuses on engineering attenuated polioviruses for oncolytic applications.

Latest Patents

One of her latest patents involves a novel and stable attenuated poliovirus that replicates in neuroblastoma cells. This innovative approach is achieved by engineering an indigenous replication element (cre) into the 5' non-translated genomic region while inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus has shown effectiveness in a neuroblastoma model (Neuro-2a tumors) that expresses CD155, the poliovirus receptor. This advancement holds promise for oncolytic treatment and potential cures for solid tumors, such as neuroblastoma.

Career Highlights

Aniko V Paul is affiliated with the State University of New York, where she continues her research and development efforts. Her work has garnered attention in the scientific community for its innovative approach to cancer treatment.

Collaborations

Aniko has collaborated with notable researchers in her field, including Eckard Wimmer and Jeronimo Cello. These collaborations have further enhanced her research and contributed to the advancement of oncolytic virus therapies.

Conclusion

Aniko V Paul is a trailblazer in the field of oncolytic virus research, with her innovative patents paving the way for new cancer treatments. Her contributions are vital to the ongoing efforts to combat solid tumors, particularly neuroblastoma.