This inventor holds 2 USPTO granted patents. Top assignees: Louisiana State University and Agricultural & Mechanical College, Torrey Pines Institute for Molecular Studies. Active years: 2006-2009.
Company Filing History:
2 out of 838 
1 out of 45 Years Active: 2006-2009
Title: Innovations of Angus Cameron in Furin Inhibition
Introduction
Angus Cameron is a notable inventor based in Bristol, GB. He has made significant contributions to the field of biochemistry, particularly in the development of peptides that inhibit furin, an important enzyme in various biological processes. With a total of 2 patents, Cameron's work has implications for therapeutic applications in treating bacterial infections, viral infections, and cancers.
Latest Patents
Cameron's latest patents focus on the use of small, polybasic peptides as effective furin inhibitors. These peptides, ranging from hexa- to nona-peptides, predominantly feature L-Arg or L-Lys in their structure. Notably, removing the peptide terminating groups enhances the inhibition of furin. High levels of inhibition have been observed in a series of non-amidated and non-acetylated polyarginines. The most potent inhibitor identified to date is nona-L-arginine, which has a K against furin of 40 nM. Non-acetylated, poly-D-arginine-derived molecules are preferred for therapeutic uses due to their non-immunogenic nature and efficient transport across cell membranes.
Career Highlights
Throughout his career, Angus Cameron has worked with prestigious institutions such as Louisiana State University and Agricultural & Mechanical College and Torrey Pines Institute for Molecular Studies. His research has significantly advanced the understanding of peptide-based inhibitors and their potential applications in medicine.
Collaborations
Cameron has collaborated with notable colleagues, including Iris Lindberg and Richard Allen Houghten. These partnerships have contributed to the depth and breadth of his research in the field of biochemistry.
Conclusion
Angus Cameron's innovative work in developing polybasic peptides as furin inhibitors showcases his expertise and dedication to advancing medical science. His contributions have the potential to lead to significant therapeutic advancements in treating various diseases.