Angelo S Mao

Title: The Innovations of Angelo S. Mao

Introduction

Angelo S. Mao is a prominent inventor based in Cambridge, MA, known for his significant contributions to the field of biomedical engineering. With a total of three patents to his name, he has made remarkable strides in advancing medical technologies that enhance immune reconstitution and promote hematopoiesis.

Latest Patents

One of his latest patents is titled "Recapitulating the hematopoietic niche to reconstitute immunity." This invention discloses compositions and related methods for recapitulating bone marrow stroma using scaffold materials, such as a porous alginate hydrogel scaffold. These compositions contain one or more cellular differentiation factors and growth factors, which promote the formation of an ectopic nodule or site. This innovation aims to improve transplanted cell engraftment and selectively drive the development of lymphocytes, thereby aiding in the reconstitution of adaptive immunity after hematopoietic stem cell transplants.

Another notable patent is "Hydrogel compositions comprising encapsulated cells and methods of use thereof." This invention provides injectable compositions that include cells encapsulated in hydrogel capsules, along with methods for preparing these compositions. The methods outlined in this patent are designed to promote hematopoiesis and treat or prevent cardiovascular and immunological disorders in subjects.

Career Highlights

Angelo S. Mao has worked with prestigious institutions, including Harvard College and The General Hospital Corporation. His work in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Throughout his career, he has collaborated with notable individuals such as David J. Mooney and Stefanie Utech. These collaborations have further enriched his research and innovations in the biomedical field.

Conclusion

Angelo S. Mao's contributions to biomedical engineering through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in medical technologies that can significantly impact patient care and treatment outcomes.