Angelika Roesler

Title: **Angelika Roesler: Innovator in Molecular Analysis**

Introduction

Angelika Roesler, an accomplished inventor based in Sindelsdorf, Germany, has made significant contributions to the field of molecular analysis. With a total of 8 patents, her work primarily focuses on advancing techniques in cancer treatment through innovative methodologies in genomic DNA analysis.

Latest Patents

Among her latest inventions, Roesler's patent for "High resolution melting analysis as a prescreening tool" stands out. This invention details a method for determining the likelihood of a patient's response to targeted cancer treatments. The process involves isolating genomic DNA from patient samples, amplifying DNA fragments using PCR with specific amplification primers, and utilizing High Resolution Melting Analysis (HRM) to identify mutations. The invention correlates these mutations with treatment success probabilities, with claims also covering respective primer pairs, compositions, and kits.

Another notable patent is for "Solid support for high-throughput nucleic acid analysis." This invention provides a solid support, such as beads, that contain two sequence-specific amplification primers, with at least one primer attached via an inducible cleavable linker. Various methods for preparing this solid support are also described, ensuring flexibility and efficiency in nucleic acid analysis.

Career Highlights

Roesler has a rich professional background, having worked with leading companies in the biotechnology sector, including Roche Molecular Systems, Inc. and Roche Diagnostics Operations, Inc. Her innovations have played a pivotal role in enhancing diagnostic methodologies, particularly in cancer research.

Collaborations

Throughout her career, Roesler has collaborated with notable colleagues such as Dieter Heindl and Thomas Froehlich. These partnerships have contributed to the advancement of innovative solutions within molecular diagnostics and have facilitated the successful development and patenting of her inventions.

Conclusion

Angelika Roesler's work exemplifies the critical intersection of innovation and healthcare. Her patents not only reflect her expertise but also her commitment to improving cancer treatment methodologies. As an inventor, Roesler continues to inspire future advancements in molecular analysis and diagnostics, making a lasting impact on the field.