The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Jan. 22, 2013
Thomas Froehlich, Bichl, DE;
Dieter Heindl, Paehl, DE;
Angelika Roesler, Sindelsdorf, DE;
Tobias Heckel, Munich, DE;
Thomas Froehlich, Bichl, DE;
Dieter Heindl, Paehl, DE;
Angelika Roesler, Sindelsdorf, DE;
Tobias Heckel, Munich, DE;
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Abstract
The present invention is directed to method for analyzing multiple nucleic acid molecules of interest comprising in the steps of (i) providing a plurality of beads, characterized in that each bead comprises at least two sequence specific amplification primers, further characterized in that at least one of the primers is bound to the bead via a cleavable linker, (ii) capturing the nucleic acid molecules of interest from a sample, (iii) clonally isolating the plurality of beads, (iv) cleaving the at least one primer, (v) clonally amplifying the nucleic acid thereby creating multiple amplification products, and (vi) analyzing the amplification products.