Jamestown, NC, United States of America

Angela S Seamans


Average Co-Inventor Count = 7.0

ph-index = 3

Forward Citations = 57(Granted Patents)


Company Filing History:


Years Active: 2005-2011

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4 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Angela S. Seamans

Introduction

Angela S. Seamans, a prominent inventor based in Jamestown, NC, has made significant strides in the field of pharmacology, particularly focusing on compounds that interact with nicotinic acetylcholinergic receptors (nAChRs). With a total of four patents to her name, Seamans has emerged as a pivotal figure in developing pharmaceutical compositions aimed at treating various conditions associated with nervous system dysfunction.

Latest Patents

Among her latest inventions are two notable patents focusing on 3-substituted-2(arylalkyl)-1-azabicycloalkanes. The first patent addresses pharmaceutical compositions that comprise compounds capable of modulating specific nAChR subtypes, particularly the α7 nAChR subtype. This invention opens avenues for treating a plethora of conditions linked to disruptions in the central and autonomic nervous systems. The second patent expands on this discovery by detailing methods of preparing these compounds and their therapeutic applications for CNS disorders characterized by altered neurotransmission. Additionally, the invention encompasses strategies for treating inflammation, autoimmune disorders, pain, and excessive neovascularization, such as that seen in tumor growth.

Career Highlights

Angela's innovative prowess is backed by her affiliation with Targacept, Inc., a company focused on developing novel therapeutic approaches for neurological and psychiatric disorders. Her work at Targacept highlights her commitment to advancing the understanding and treatment of complex medical conditions, leveraging her expertise in pharmacology and medicinal chemistry.

Collaborations

Throughout her career, Angela has collaborated with talented professionals, including Anatoly A. Mazurov and Jozef Klucik. These partnerships reflect a collaborative spirit essential in the research and development sector, fostering innovation through shared knowledge and expertise.

Conclusion

Angela S. Seamans exemplifies the impact of innovation in medicine through her extensive research on nAChRs and the development of novel therapeutic compounds. Her contributions not only enhance our understanding of neurotransmission but also pave the way for promising treatments for a variety of conditions affecting the nervous system. With her ongoing work at Targacept, the future of pharmacological innovations looks promising under her guidance.

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