Angela Ruth Melton-Celsa

Title: Innovations of Angela Ruth Melton-Celsa

Introduction

Angela Ruth Melton-Celsa is a notable inventor based in Sterling, Virginia. She has made significant contributions to the field of medical research, particularly in the area of Shiga toxin type 2 protein. With a total of five patents to her name, her work has the potential to impact the treatment of diseases associated with this toxin.

Latest Patents

One of her latest patents focuses on methods and compositions based on Shiga toxin type 2 protein. This invention is based on the discovery of the epitope in the Stx2 protein for the 11 E1O antibody. The invention features compositions containing non-full length Stx2 polypeptides that include the 11 E1O monoclonal antibody epitope. Additionally, it includes methods of producing anti-Stx2 antibodies specific for the 11 E1O epitope of the Stx2 protein. Furthermore, the invention outlines methods for treating subjects who have, or are at risk of developing, a Shiga toxin-associated disease, such as hemolytic uremic syndrome. It also provides methods for detecting Stx2 in a sample using the antibodies developed through her innovative methods.

Career Highlights

Throughout her career, Angela has worked with esteemed organizations, including the Henry M. Jackson Foundation for the Advancement of Military Medicine and Sunol Molecular Corporation. Her experience in these institutions has allowed her to collaborate with other professionals in the field and contribute to groundbreaking research.

Collaborations

Some of her notable coworkers include Alison D. O'Brien and Michael Smith. Their collaborative efforts have further advanced the research and development of her inventions.

Conclusion

Angela Ruth Melton-Celsa's innovative work in the field of Shiga toxin type 2 protein exemplifies her dedication to medical research and invention. Her contributions have the potential to significantly improve treatment options for diseases associated with this toxin.