Andrew Leonard Lewis

Title: **Andrew Leonard Lewis: Innovator in Biomedical Engineering**

Introduction

Andrew Leonard Lewis, an accomplished inventor based in Surrey, GB, has made significant contributions to the field of biomedical engineering. With two registered patents to his name, Lewis focuses on developing advanced materials and methods that enhance medical procedures and treatment options for patients.

Latest Patents

Lewis's most recent inventions include the following:

1. **Imageable Embolic Microsphere**: This innovative patent revolves around the creation of imageable and radiopaque embolic beads. These beads are particularly beneficial for monitoring embolization procedures, as they incorporate iodine-containing compounds covalently within a preformed hydrogel bead. The methodology of this invention involves activating pre-formed hydrogel beads for nucleophilic attack, followed by covalent attachment of iodinated compounds into the polymer network. Additionally, these radiopaque beads can be loaded with chemotherapeutic agents, making them applicable for embolizing hyperplastic tissue or solid tumors.

2. **Drug Carriers Comprising Amphiphilic Block Copolymers**: This patent describes an aqueous composition that includes an amphiphilic block copolymer. The copolymer features a hydrophilic block with pendant zwitterionic groups and a hydrophobic block. A biologically active compound, preferably a hydrophobic drug, is associated with the polymer, likely formed into micelles. The method for producing micelles involves dissolving the copolymer at a protonated pH, followed by increasing the pH to induce spontaneous micelle formation. This innovative approach provides a new avenue for tumor treatment applications.

Career Highlights

Throughout his career, Andrew Leonard Lewis has been associated with prominent organizations, one of which is Biocompatible UK Limited. His work there involved pushing the boundaries of biocompatible materials for medical applications. Additionally, he has collaborated with the National Institutes of Health, contributing to advanced research initiatives and bringing innovative solutions to the biomedical field.

Collaborations

Lewis has worked alongside renowned colleagues, including Matthew R. Dreher and Bradford Johns Wood. Their collaboration has facilitated the exchange of ideas and research, further propelling their joint contributions to innovations in biomedical engineering.

Conclusion

Andrew Leonard Lewis exemplifies the spirit of innovation in the realm of biomedical engineering. His patents on imageable embolic microspheres and drug carriers demonstrate his commitment to advancing medical technology. As he continues his work, the impact of his inventions on patient treatment and monitoring promises to be substantial, solidifying his legacy as a significant inventor in the field.