The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 14, 2014
Biocompatibles Uk Limited, Surrey, GB;
Matthew R. Dreher, West Conshohocken, PA (US);
Bradford J. Wood, Bethesda, MD (US);
Ayele H. Negussie, Bethesda, MD (US);
Andrew Leonard Lewis, Surrey, GB;
Yiqing Tang, Surrey, GB;
Matthew R. Dreher, West Conshohocken, PA (US);
Bradford J. Wood, Bethesda, MD (US);
Ayele H. Negussie, Bethesda, MD (US);
Andrew Leonard Lewis, Surrey, GB;
Yiqing Tang, Surrey, GB;
Biocompatible UK Limited, Farnham, Surrey, GB;
National Institutes of Health, Bethesda, MD (US);
Abstract
This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hydrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors.